The Circuits and Biology Lab at UMN - Recent changes [en]

Papers, Presentations, Theses, and Patents

MarcRiedel — Thu, 20 Aug 2026 16:53:40 GMT

Use fresh source-crop filenames to prevent stale publication thumbnails

File:Desai Data Cycling Application Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:40 GMT

MarcRiedel uploaded File:Desai Data Cycling Application Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Jiang Molecular Moving Average Filter Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:39 GMT

MarcRiedel uploaded File:Jiang Molecular Moving Average Filter Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Salehi Molecular Computation Methodology Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:39 GMT

MarcRiedel uploaded File:Salehi Molecular Computation Methodology Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-networks-of-passive-oscillators-b460bb37-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:39 GMT

MarcRiedel uploaded File:Riedel-research-networks-of-passive-oscillators-b460bb37-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:38 GMT

MarcRiedel uploaded File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:38 GMT

MarcRiedel uploaded File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-estimation-and-optimization-of-reliability-of-noisy-digital-circuits-86a73b03-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:37 GMT

MarcRiedel uploaded File:Riedel-research-estimation-and-optimization-of-reliability-of-noisy-digital-circuits-86a73b03-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-a-reconfigurable-architecture-with-sequential-logic-based-stochastic-com-65434e2e-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:37 GMT

MarcRiedel uploaded File:Riedel-research-a-reconfigurable-architecture-with-sequential-logic-based-stochastic-com-65434e2e-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Focused Stochastic Image Processing Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:36 GMT

MarcRiedel uploaded File:Focused Stochastic Image Processing Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Focused Linear Finite State Machines Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:36 GMT

MarcRiedel uploaded File:Focused Linear Finite State Machines Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:35 GMT

MarcRiedel uploaded File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-the-synthesis-of-robust-polynomial-arithmetic-with-stochastic-logic-c16b112d-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:35 GMT

MarcRiedel uploaded File:Riedel-research-the-synthesis-of-robust-polynomial-arithmetic-with-stochastic-logic-c16b112d-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-the-synthesis-of-stochastic-logic-to-perform-multivariate-polynomial-ari-65ce4570-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:34 GMT

MarcRiedel uploaded File:Riedel-research-the-synthesis-of-stochastic-logic-to-perform-multivariate-polynomial-ari-65ce4570-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-tolerating-faults-in-counting-networks-603ade56-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:34 GMT

MarcRiedel uploaded File:Riedel-research-tolerating-faults-in-counting-networks-603ade56-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Riedel-research-characterizing-polynomial-arithmetic-with-stochastic-circuits-95c17add-figure-v2.jpg

MarcRiedel — Thu, 20 Aug 2026 16:53:33 GMT

MarcRiedel uploaded File:Riedel-research-characterizing-polynomial-arithmetic-with-stochastic-circuits-95c17add-figure-v2.jpg Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

File:Kaslewicz Random Access DNA Registers Source Crop.png

MarcRiedel — Thu, 20 Aug 2026 16:53:33 GMT

MarcRiedel uploaded File:Kaslewicz Random Access DNA Registers Source Crop.png Add source-native crop for the publications page

New page

== Source ==
Figure excerpted from the linked paper or thesis. Marc Riedel is an author or adviser.

Papers, Presentations, Theses, and Patents

MarcRiedel — Thu, 20 Aug 2026 16:49:13 GMT

Standardize figure width and refine requested publication and thesis visuals

← Older revision		Revision as of 16:49, 20 August 2026
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	<table style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;">		<table style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;">
	<tr valign="middle">		<tr valign="middle">
	<td style="width:~~400px~~; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;">[[Image:Kaslewicz_Random_Access_DNA_Registers.png\|~~380px~~]]</td>		<td style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;">[[Image:Kaslewicz_Random_Access_DNA_Registers.png\|280px]]</td>
	<td style="padding:0 0 0 22px;">		<td style="padding:0 0 0 22px;">
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/4/4c/Kaslewicz_jake_random_access_dna_registers.pdf Random Access DNA Registers]'''</span><br>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/4/4c/Kaslewicz_jake_random_access_dna_registers.pdf Random Access DNA Registers]'''</span><br>

File:Desai Data Cycling Communication Cycle.png

MarcRiedel — Thu, 20 Aug 2026 16:49:12 GMT

MarcRiedel uploaded a new version of File:Desai Data Cycling Communication Cycle.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

Representative figure extracted from the thesis

File:Jiang Molecular Moving Average Filter.png

MarcRiedel — Thu, 20 Aug 2026 16:49:12 GMT

MarcRiedel uploaded a new version of File:Jiang Molecular Moving Average Filter.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

Representative figure extracted from the thesis

File:Salehi Molecular Computation Methodology.png

MarcRiedel — Thu, 20 Aug 2026 16:49:11 GMT

MarcRiedel uploaded a new version of File:Salehi Molecular Computation Methodology.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

Representative figure extracted from the thesis

File:Riedel-research-networks-of-passive-oscillators-b460bb37.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:11 GMT

MarcRiedel uploaded a new version of File:Riedel-research-networks-of-passive-oscillators-b460bb37.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Networks of Passive Oscillators''. Marc Riedel is an author of the paper.

File:Riedel-research-estimation-and-optimization-of-reliability-of-noisy-digital-circuits-86a73b03.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:10 GMT

MarcRiedel uploaded a new version of File:Riedel-research-estimation-and-optimization-of-reliability-of-noisy-digital-circuits-86a73b03.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Estimation and Optimization of Reliability of Noisy Digital Circuits''. Marc Riedel is an author of the paper.

File:Riedel-research-a-reconfigurable-architecture-with-sequential-logic-based-stochastic-com-65434e2e.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:10 GMT

MarcRiedel uploaded a new version of File:Riedel-research-a-reconfigurable-architecture-with-sequential-logic-based-stochastic-com-65434e2e.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''A Reconfigurable Architecture with Sequential Logic-Based Stochastic Computing''. Marc Riedel is an author of the paper.

File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:10 GMT

MarcRiedel uploaded a new version of File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Logic Synthesis for Switching Lattices''. Marc Riedel is an author of the paper.

File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:10 GMT

MarcRiedel uploaded a new version of File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Synthesizing Cubes to Satisfy a Given Intersection Pattern''. Marc Riedel is an author of the paper.

File:Focused Stochastic Image Processing.png

MarcRiedel — Thu, 20 Aug 2026 16:49:09 GMT

MarcRiedel uploaded a new version of File:Focused Stochastic Image Processing.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

File:Focused Linear Finite State Machines.png

MarcRiedel — Thu, 20 Aug 2026 16:49:09 GMT

MarcRiedel uploaded a new version of File:Focused Linear Finite State Machines.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:08 GMT

MarcRiedel uploaded a new version of File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''The Synthesis of Stochastic Circuits for Nanoscale Computation''. Marc Riedel is an author of the paper.

File:Riedel-research-the-synthesis-of-robust-polynomial-arithmetic-with-stochastic-logic-c16b112d.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:08 GMT

MarcRiedel uploaded a new version of File:Riedel-research-the-synthesis-of-robust-polynomial-arithmetic-with-stochastic-logic-c16b112d.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''The Synthesis of Robust Polynomial Arithmetic with Stochastic Logic''. Marc Riedel is an author of the paper.

File:Riedel-research-the-synthesis-of-stochastic-logic-to-perform-multivariate-polynomial-ari-65ce4570.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:08 GMT

MarcRiedel uploaded a new version of File:Riedel-research-the-synthesis-of-stochastic-logic-to-perform-multivariate-polynomial-ari-65ce4570.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''The Synthesis of Stochastic Logic to Perform Multivariate Polynomial Arithmetic''. Marc Riedel is an author of the paper.

File:Riedel-research-tolerating-faults-in-counting-networks-603ade56.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:07 GMT

MarcRiedel uploaded a new version of File:Riedel-research-tolerating-faults-in-counting-networks-603ade56.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Tolerating Faults in Counting Networks''. Marc Riedel is an author of the paper.

File:Riedel-research-characterizing-polynomial-arithmetic-with-stochastic-circuits-95c17add.jpg

MarcRiedel — Thu, 20 Aug 2026 16:49:07 GMT

MarcRiedel uploaded a new version of File:Riedel-research-characterizing-polynomial-arithmetic-with-stochastic-circuits-95c17add.jpg Use a tighter, source-native crop and preserve the figure aspect ratio

New page

== Source ==
Figure excerpted from ''Characterizing Polynomial Arithmetic with Stochastic Circuits''. Marc Riedel is an author of the paper.

File:Kaslewicz Random Access DNA Registers.png

MarcRiedel — Thu, 20 Aug 2026 16:49:07 GMT

MarcRiedel uploaded a new version of File:Kaslewicz Random Access DNA Registers.png Use a tighter, source-native crop and preserve the figure aspect ratio

New page

Representative figure extracted from the thesis

Papers, Presentations, Theses, and Patents

MarcRiedel — Thu, 20 Aug 2026 16:28:05 GMT

Improve requested figures, enlarge Random Access DNA Registers image, and remove thesis-end montage

← Older revision		Revision as of 16:28, 20 August 2026
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	<table style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;">		<table style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;">
	<tr valign="middle">		<tr valign="middle">
	<td style="width:~~300px~~; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;">[[Image:Kaslewicz_Random_Access_DNA_Registers.png\|~~280px~~]]</td>		<td style="width:400px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;">[[Image:Kaslewicz_Random_Access_DNA_Registers.png\|380px]]</td>
	<td style="padding:0 0 0 22px;">		<td style="padding:0 0 0 22px;">
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/4/4c/Kaslewicz_jake_random_access_dna_registers.pdf Random Access DNA Registers]'''</span><br>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/4/4c/Kaslewicz_jake_random_access_dna_registers.pdf Random Access DNA Registers]'''</span><br>
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	</table>		</table>

	<br>
	-----
	<br>
	[[Image:website-art-4.png\|center\|500px]]

	== Patents ==		== Patents ==

File:Cheng Stochastic Transient Analysis.png

MarcRiedel — Thu, 20 Aug 2026 16:28:04 GMT

MarcRiedel uploaded a new version of File:Cheng Stochastic Transient Analysis.png Improve figure crop and visual choice on the publications page

New page

Representative figure extracted from the thesis

File:Improved Stochastic Transient Analysis.png

MarcRiedel — Thu, 20 Aug 2026 16:28:04 GMT

MarcRiedel uploaded a new version of File:Improved Stochastic Transient Analysis.png Improve figure crop and visual choice on the publications page

New page

File:Backes Thesis Topics.png

MarcRiedel — Thu, 20 Aug 2026 16:28:03 GMT

MarcRiedel uploaded a new version of File:Backes Thesis Topics.png Improve figure crop and visual choice on the publications page

New page

Representative figure extracted from the thesis

File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757.jpg

MarcRiedel — Thu, 20 Aug 2026 16:28:03 GMT

MarcRiedel uploaded a new version of File:Riedel-research-synthesizing-cubes-to-satisfy-a-given-intersection-pattern-ca411757.jpg Improve figure crop and visual choice on the publications page

New page

== Source ==
Figure excerpted from ''Synthesizing Cubes to Satisfy a Given Intersection Pattern''. Marc Riedel is an author of the paper.

File:Dormuth DNA Storage and Computation.png

MarcRiedel — Thu, 20 Aug 2026 16:28:03 GMT

MarcRiedel uploaded a new version of File:Dormuth DNA Storage and Computation.png Improve figure crop and visual choice on the publications page

New page

Representative figure extracted from the thesis

File:Salehi Molecular Computation Methodology.png

MarcRiedel — Thu, 20 Aug 2026 16:28:02 GMT

MarcRiedel uploaded a new version of File:Salehi Molecular Computation Methodology.png Improve figure crop and visual choice on the publications page

New page

Representative figure extracted from the thesis

File:Jiang Molecular Moving Average Filter.png

MarcRiedel — Thu, 20 Aug 2026 16:28:02 GMT

MarcRiedel uploaded a new version of File:Jiang Molecular Moving Average Filter.png Improve figure crop and visual choice on the publications page

New page

Representative figure extracted from the thesis

File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac.jpg

MarcRiedel — Thu, 20 Aug 2026 16:28:02 GMT

MarcRiedel uploaded a new version of File:Riedel-research-the-synthesis-of-stochastic-circuits-for-nanoscale-computation-4ffd4fac.jpg Improve figure crop and visual choice on the publications page

New page

== Source ==
Figure excerpted from ''The Synthesis of Stochastic Circuits for Nanoscale Computation''. Marc Riedel is an author of the paper.

File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6.jpg

MarcRiedel — Thu, 20 Aug 2026 16:28:01 GMT

MarcRiedel uploaded a new version of File:Riedel-research-logic-synthesis-for-switching-lattices-65f5e4f6.jpg Improve figure crop and visual choice on the publications page

New page

== Source ==
Figure excerpted from ''Logic Synthesis for Switching Lattices''. Marc Riedel is an author of the paper.

File:Riedel-research-synthesis-of-polynomial-functions-80f08673.jpg

MarcRiedel — Thu, 20 Aug 2026 16:28:01 GMT

MarcRiedel uploaded a new version of File:Riedel-research-synthesis-of-polynomial-functions-80f08673.jpg Improve figure crop and visual choice on the publications page

New page

== Source ==
Figure excerpted from ''Synthesis of Polynomial Functions''. Marc Riedel is an author of the paper.

Papers, Presentations, Theses, and Patents

MarcRiedel — Wed, 19 Aug 2026 14:48:45 GMT

← Older revision		Revision as of 14:48, 19 August 2026
(2 intermediate revisions by the same user not shown)
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	__NOTOC__		__NOTOC__
			Here is a curated set of our publications, each with an playful, sometimes whimsical, description of its content and impact. Where different versions of a paper have been published in different venues, say first in conference proceedings and then in a journal, these are grouped together in one entry.

	The projects below are grouped by the question they ask rather than the venue in which the answer appeared. Conference and journal versions of the same work share one account.

	== Storing with Molecules ==		== Storing with Molecules ==
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
			\|- valign="middle"
	\|-
			\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Riedel-research-evasive-spike-variants-elucidate-the-preservation-of-t-cell-immune-260699b3.jpg\|frameless\|280px\|alt=Evasive Spike Variants Elucidate the Preservation of T cell Immune Response to the SARS-CoV-2 Omicron Variant\|link=https://mriedel.ece.umn.edu/wiki/images/1/12/Evasive_Spike_Variants_Elucidate_the_Preservation_of_T_Cell_Immune_Response_to_the_SARS-CoV-2_Omicron_Variant.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[[Media:Evasive_Spike_Variants_Elucidate_the_Preservation_of_T_Cell_Immune_Response_to_the_SARS-CoV-2_Omicron_Variant.pdf\|Evasive Spike Variants Elucidate the Preservation of T cell Immune Response to the SARS-CoV-2 Omicron Variant]]'''</span>		<span style="font-size:115%;">'''[[Media:Evasive_Spike_Variants_Elucidate_the_Preservation_of_T_Cell_Immune_Response_to_the_SARS-CoV-2_Omicron_Variant.pdf\|Evasive Spike Variants Elucidate the Preservation of T cell Immune Response to the SARS-CoV-2 Omicron Variant]]'''</span>
	<br><span class="paper-meta" style="display:inline-block; margin-top:0.3em; font-size:98%; line-height:1.4;"><b>Authors:</b> Arnav Solanki, James Cornette, Julia Udell, George Vasmatzis, and Marc Riedel<br><b>Venue:</b> <i>IEEE/ACM TCBB (2024)</i></span>		<br><span class="paper-meta" style="display:inline-block; margin-top:0.3em; font-size:98%; line-height:1.4;"><b>Authors:</b> Arnav Solanki, James Cornette, Julia Udell, George Vasmatzis, and Marc Riedel<br><b>Venue:</b> <i>IEEE/ACM TCBB (2024)</i></span>

			A dog that did not bark is evidence only once you know the dog can bark. Omicron’s spike carries enough mutations to slip past most neutralizing antibodies, yet T cell responses to it hold up—reassuring, but hard to interpret, since “no loss detected” may only mean the instrument was not looking. This paper runs the natural variants and the vaccine spikes through NetMHCpan-4.1 and NetMHCiipan-4.0 and finds their Class I and Class II antigen repertoires essentially unchanged: the mutations swap which peptides are presented without reducing how many. Then comes the control. The authors engineer two hundred “evader” spikes, each allotted exactly BA.1’s budget of thirty-six mutations but spent deliberately, on anchor residues, substituting amino acids that the relevant binding pocket refuses. The evaders collapse antigenicity across nearly every HLA tested and separate cleanly from the natural variants, while Omicron sits comfortably among them. Evasion of the T cell pathway was thus within reach of the virus’s mutation budget; Omicron simply did not spend it that way. The paper’s durable move is the control itself: to give a negative result teeth, build the positive result that should have happened.

	<small>'''[[Media:Evasive_Spike_Variants_Elucidate_the_Preservation_of_T_Cell_Immune_Response_to_the_SARS-CoV-2_Omicron_Variant.pdf\|PDF]]'''</small>		<small>'''[[Media:Evasive_Spike_Variants_Elucidate_the_Preservation_of_T_Cell_Immune_Response_to_the_SARS-CoV-2_Omicron_Variant.pdf\|PDF]]'''</small>

File:Riedel-research-evasive-spike-variants-elucidate-the-preservation-of-t-cell-immune-260699b3.jpg

MarcRiedel — Wed, 19 Aug 2026 13:12:30 GMT

MarcRiedel uploaded File:Riedel-research-evasive-spike-variants-elucidate-the-preservation-of-t-cell-immune-260699b3.jpg Figure 4 from Solanki, Cornette, Udell, Vasmatzis, and Riedel, "Evasive Spike Variants Elucidate the Preservation of T cell Immune Response to the SARS-CoV-2 Omicron Variant," IEEE/ACM TCBB (2024). Thumbnail for the Publications page.

New page

== Summary ==
Figure 4 from Solanki, Cornette, Udell, Vasmatzis, and Riedel, "Evasive Spike Variants Elucidate the Preservation of T cell Immune Response to the SARS-CoV-2 Omicron Variant," IEEE/ACM TCBB (2024). Thumbnail for the Publications page.

Papers, Presentations, Theses, and Patents

MarcRiedel — Wed, 19 Aug 2026 02:27:09 GMT

Focus selected figures, center cyclic-dependency graphic, and remove repeated circuit image

← Older revision		Revision as of 02:27, 19 August 2026
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
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	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-automated-routing-of-droplets-for-dna-storage-on-a-digital-microfluidics-e887e859~~.~~jpg~~\|frameless\|280px\|alt=Automated Routing of Droplets for DNA Storage on a Digital Microfluidics Platform\|link=https://pubs.rsc.org/en/content/articlelanding/2023/dd/d3dd00083d]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Improved_Automated_Droplet_Routing_Web.png\|frameless\|280px\|alt=Automated Routing of Droplets for DNA Storage on a Digital Microfluidics Platform\|link=https://pubs.rsc.org/en/content/articlelanding/2023/dd/d3dd00083d]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://pubs.rsc.org/en/content/articlelanding/2023/dd/d3dd00083d Automated Routing of Droplets for DNA Storage on a Digital Microfluidics Platform]'''</span>		<span style="font-size:115%;">'''[https://pubs.rsc.org/en/content/articlelanding/2023/dd/d3dd00083d Automated Routing of Droplets for DNA Storage on a Digital Microfluidics Platform]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
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	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-low-cost-sorting-network-circuits-using-unary-processing-e0f1271f~~.~~jpg~~\|frameless\|280px\|alt=Low-Cost Sorting Network Circuits Using Unary Processing\|link=https://cctbio.ece.umn.edu/wiki/images/c/cc/Najafi_Lilja_Riedel_Bazargan_Low_Cost_Sorting_Network_Circuits_using_Unary_Processing.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Focused_Unary_Sorting_Comparison.png\|frameless\|280px\|alt=Low-Cost Sorting Network Circuits Using Unary Processing\|link=https://cctbio.ece.umn.edu/wiki/images/c/cc/Najafi_Lilja_Riedel_Bazargan_Low_Cost_Sorting_Network_Circuits_using_Unary_Processing.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://cctbio.ece.umn.edu/wiki/images/c/cc/Najafi_Lilja_Riedel_Bazargan_Low_Cost_Sorting_Network_Circuits_using_Unary_Processing.pdf Low-Cost Sorting Network Circuits Using Unary Processing]'''</span>		<span style="font-size:115%;">'''[https://cctbio.ece.umn.edu/wiki/images/c/cc/Najafi_Lilja_Riedel_Bazargan_Low_Cost_Sorting_Network_Circuits_using_Unary_Processing.pdf Low-Cost Sorting Network Circuits Using Unary Processing]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
	\|- valign="middle"		\|- valign="middle"
	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-polysynchronous-clocking-exploiting-the-skew-tolerance-of-stochastic-cir-59e05f4a~~.~~jpg~~\|frameless\|280px\|alt=Polysynchronous Clocking: Exploiting the Skew Tolerance of Stochastic Circuits\|link=https://mriedel.ece.umn.edu/wiki/images/1/13/Najafi_Lilja_Riedel_Bazargan_Polysynchronous_Clocking_Exploiting_the_Skew_Tolerance_of_Stochastic_Circuits.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Focused_Polysynchronous_Clocking.png\|frameless\|280px\|alt=Polysynchronous Clocking: Exploiting the Skew Tolerance of Stochastic Circuits\|link=https://mriedel.ece.umn.edu/wiki/images/1/13/Najafi_Lilja_Riedel_Bazargan_Polysynchronous_Clocking_Exploiting_the_Skew_Tolerance_of_Stochastic_Circuits.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/1/13/Najafi_Lilja_Riedel_Bazargan_Polysynchronous_Clocking_Exploiting_the_Skew_Tolerance_of_Stochastic_Circuits.pdf Polysynchronous Clocking: Exploiting the Skew Tolerance of Stochastic Circuits]'''</span>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/1/13/Najafi_Lilja_Riedel_Bazargan_Polysynchronous_Clocking_Exploiting_the_Skew_Tolerance_of_Stochastic_Circuits.pdf Polysynchronous Clocking: Exploiting the Skew Tolerance of Stochastic Circuits]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
	\|- valign="middle"		\|- valign="middle"
	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-computation-on-stochastic-bit-streams-digital-image-processing-case-stud-52023a3a~~.~~jpg~~\|frameless\|280px\|alt=Computation on Stochastic Bit Streams: Digital Image Processing Case Studies\|link=https://mriedel.ece.umn.edu/wiki/images/f/f7/Li_Lilja_Qian_Bazargan_Riedel_Computation_on_Stochastic_Bit_Streams_Digital_Image_Processing_Case_Studies.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Focused_Stochastic_Image_Processing.png\|frameless\|280px\|alt=Computation on Stochastic Bit Streams: Digital Image Processing Case Studies\|link=https://mriedel.ece.umn.edu/wiki/images/f/f7/Li_Lilja_Qian_Bazargan_Riedel_Computation_on_Stochastic_Bit_Streams_Digital_Image_Processing_Case_Studies.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/f/f7/Li_Lilja_Qian_Bazargan_Riedel_Computation_on_Stochastic_Bit_Streams_Digital_Image_Processing_Case_Studies.pdf Computation on Stochastic Bit Streams: Digital Image Processing Case Studies]'''</span>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/f/f7/Li_Lilja_Qian_Bazargan_Riedel_Computation_on_Stochastic_Bit_Streams_Digital_Image_Processing_Case_Studies.pdf Computation on Stochastic Bit Streams: Digital Image Processing Case Studies]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
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	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-logical-computation-on-stochastic-bit-streams-with-linear-finite-state-m-75158ccd~~.~~jpg~~\|frameless\|280px\|alt=Logical Computation on Stochastic Bit Streams with Linear Finite-State Machines\|link=https://mriedel.ece.umn.edu/wiki/images/7/7c/Li_Lilja_Qian_Riedel_Bazargan_Logical_Computation_on_Stochastic_Bit_Streams_with_Linear_Finite_State_Machines.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Focused_Linear_Finite_State_Machines.png\|frameless\|280px\|alt=Logical Computation on Stochastic Bit Streams with Linear Finite-State Machines\|link=https://mriedel.ece.umn.edu/wiki/images/7/7c/Li_Lilja_Qian_Riedel_Bazargan_Logical_Computation_on_Stochastic_Bit_Streams_with_Linear_Finite_State_Machines.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/7/7c/Li_Lilja_Qian_Riedel_Bazargan_Logical_Computation_on_Stochastic_Bit_Streams_with_Linear_Finite_State_Machines.pdf Logical Computation on Stochastic Bit Streams with Linear Finite-State Machines]'''</span>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/7/7c/Li_Lilja_Qian_Riedel_Bazargan_Logical_Computation_on_Stochastic_Bit_Streams_with_Linear_Finite_State_Machines.pdf Logical Computation on Stochastic Bit Streams with Linear Finite-State Machines]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
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	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-the-synthesis-of-cyclic-dependencies-with-boolean-satisfiability-df729064~~.~~jpg~~\|frameless\|280px\|alt=The Synthesis of Cyclic Dependencies with Boolean Satisfiability\|link=https://mriedel.ece.umn.edu/wiki/images/8/82/Backes_Riedel_The_Synthesis_of_Cyclic_Functional_Dependencies_with_Boolean_Satisfiability.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Centered_Cyclic_Dependencies.png\|frameless\|280px\|alt=The Synthesis of Cyclic Dependencies with Boolean Satisfiability\|link=https://mriedel.ece.umn.edu/wiki/images/8/82/Backes_Riedel_The_Synthesis_of_Cyclic_Functional_Dependencies_with_Boolean_Satisfiability.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/8/82/Backes_Riedel_The_Synthesis_of_Cyclic_Functional_Dependencies_with_Boolean_Satisfiability.pdf The Synthesis of Cyclic Dependencies with Boolean Satisfiability]'''</span>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/8/82/Backes_Riedel_The_Synthesis_of_Cyclic_Functional_Dependencies_with_Boolean_Satisfiability.pdf The Synthesis of Cyclic Dependencies with Boolean Satisfiability]'''</span>
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	{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"		{\| style="width:100%; margin:0.7em 0 2.2em 0; border-collapse:collapse;"
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	\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:~~Riedel-research-the-analysis-and-mapping-of-cyclic-circuits-with-boolean-satisfiability-cb7fd102~~.~~jpg~~\|frameless\|280px\|alt=The Analysis and Mapping of Cyclic Circuits with Boolean Satisfiability\|link=https://mriedel.ece.umn.edu/wiki/images/6/66/Backes_Fett_Riedel_The_Analysis_And_Mapping_Of_Cyclic_Cricuits_With_Boolean_Satisfiability.pdf]]		\| style="width:300px; padding:10px; text-align:center; vertical-align:middle; background:linear-gradient(145deg,#ffffff 0%,#eef4fa 55%,#dce8f3 100%); border:1px solid #9fb1c2; border-radius:8px; box-shadow:inset 0 0 0 1px #ffffff, 0 3px 8px #c2ccd6;" \| [[File:Distinct_SAT_Analysis_Workflow.png\|frameless\|280px\|alt=The Analysis and Mapping of Cyclic Circuits with Boolean Satisfiability\|link=https://mriedel.ece.umn.edu/wiki/images/6/66/Backes_Fett_Riedel_The_Analysis_And_Mapping_Of_Cyclic_Cricuits_With_Boolean_Satisfiability.pdf]]
	\| style="padding:0 0 0 22px;" \|		\| style="padding:0 0 0 22px;" \|
	<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/6/66/Backes_Fett_Riedel_The_Analysis_And_Mapping_Of_Cyclic_Cricuits_With_Boolean_Satisfiability.pdf The Analysis and Mapping of Cyclic Circuits with Boolean Satisfiability]'''</span>		<span style="font-size:115%;">'''[https://mriedel.ece.umn.edu/wiki/images/6/66/Backes_Fett_Riedel_The_Analysis_And_Mapping_Of_Cyclic_Cricuits_With_Boolean_Satisfiability.pdf The Analysis and Mapping of Cyclic Circuits with Boolean Satisfiability]'''</span>