Sniffers, Buzzers, Toggles and Blinkers
From The Circuits and Biology Lab at UMN
Authors: John J. Tyson (1), Katherine C. Chen (1), and Bela Novak (2)
- Department of Biology, Virginia Polytechnic Institute and State University
- Molecular Network Dynamics Research Group, Hungarian Academy of Sciences;
and Department of Agricultural Chemical Technology, Budapest University of Technology and Economics
Abstract: The physiological responses of cells to external and internal stimuli are governed by genes and proteins interacting in complex networks whose dynamical properties are impossible to understand by intuitive reasoning alone. Recent advances by theoretical biologists have demonstrated that molecular regulatory networks can be accurately modeled in mathematical terms. These models shed light on the design principles of biological control systems and make predictions that have been verified experimentally.
Publication: Current Opinion in Cell Biology, 2003, 15:221–231.
